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CAS No. | 890090-75-2 | Cat. No. | BCP02265 |
Name | Nutlin-3 | ||
Synonyms | Nutlin 3;(+/-)-Nutlin3; | ||
SMILES | CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl | ||
Chemical Name | |||
Formula | C30H30Cl2N4O4 | M. Wt | 581.49 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 µM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches. |
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