GSK 650394
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CAS No. | 890842-28-1 | Cat. No. | BCP08392 |
Name | GSK 650394 | ||
Synonyms | GSK-650394; GSK650394; | ||
SMILES | |||
Chemical Name | |||
Formula | C25H22N2O2 | M. Wt | 382.45 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor (IC50 values are 62 and 103 nM for SGK1 and SGK2 respectively). Displays >30-fold selectivity over Akt and other related kinases. Inhibits androgen-stimulated growth of LNCaP cells, a human prostate carcinoma cell line (IC50 ~ 1 μM). |
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