MSX-122
Data Sheet
For research use only. Not for human use.
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| CAS No. | 897657-95-3 | Cat. No. | BCP16282 |
| Name | MSX-122 | ||
| Synonyms | MSX 122;MSX122; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C16H16N6 | M. Wt | 292.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MSX-122 is a n orally bioavailable inhibitor of CXCR4 with potential antineoplastic and antiviral activities. CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4, preventing the binding of stromal derived factor-1 (SDF-1) to the CXCR4 receptor and receptor activation, which may result in decreased tumor cell proliferation and migration. CXCR4, a chemokine receptor belonging to the GPCR (G protein-coupled receptor) gene family, plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types; it is also a co-receptor for HIV entry into T cells. The chemical structure of MSX-122 is very similar to that of WZ811. | ||
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