AZD1283
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CAS No. | 919351-41-0 | Cat. No. | BCP10803 |
Name | AZD1283 | ||
Synonyms | AZD-1283;AZD 1283; | ||
SMILES | |||
Chemical Name | |||
Formula | C23H26N4O5S | M. Wt | 470.54 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 μg/kg/min, respectively. The doses that induced a larger than 3-fold increase in bleeding time were 33 and 100 μg/kg/min for 3 and 13, respectively. Thus, the therapeutic index (TI) was ≥10 for both compounds. On the basis of these data, compound 3 was progressed into human clinical trials as candidate drug AZD1283. |
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