Riviciclib New
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| CAS No. | 920113-02-6 | Cat. No. | BCP17903 |
| Name | Riviciclib | ||
| Synonyms | P276-00; P-276-00; P 276-00; P-27600; P 27600; P 27600; | ||
| SMILES | CN1CCC(C1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O | ||
| Chemical Name | |||
| Formula | C21H20ClNO5 | M. Wt | 401.84 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Riviciclib, also known as P276-00 , is a flavone and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. P276-00 selectively binds to and inhibits Cdk4/cyclin D1, Cdk1/cyclin B and Cdk9/cyclin T1, serine/threonine kinases that play key roles in the regulation of the cell cycle and cellular proliferation. Inhibition of these kinases leads to cell cycle arrest during the G1/S transition, thereby leading to an induction of apoptosis, and inhibition of tumor cell proliferation. | ||
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