Amrubicin hydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 92395-36-3 | Cat. No. | BCP07436 |
| Name | Amrubicin hydrochloride | ||
| Synonyms | AMR hydrochloride;SM 5887;SM5887;SM-5887; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C25H26ClNO9 | M. Wt | 519.93 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Amrubicin hydrochloride is the hydrochloride salt of a third-generation synthetic 9-amino-anthracycline with antineoplastic activity. Amrubicin intercalates into DNA and inhibits the activity of topoisomerase II, resulting in inhibition of DNA replication, and RNA and protein synthesis, followed by cell growth inhibition and cell death. This agent has demonstrated a higher level of anti-tumor activity than conventional anthracycline drugs without exhibiting any indication of the cumulative cardiac toxicity common to this class of compounds. It is marketed in Japan since 2002 by Sumitomo Pharmaceuticals. | ||
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