Elafibranor New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP19067CAS No. ：923978-27-2Purity：98%

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CAS No.	923978-27-2	Cat. No.	BCP19067
Name	Elafibranor
Synonyms	824932-88-9;GFT505;GFT-505;GFT 505;
SMILES	CC1=CC(=CC(=C1OC(C)(C)C(=O)O)C)C=CC(=O)C2=CC=C(C=C2)SC
Chemical Name
Formula	C22H24O4S	M. Wt	384.49
Purity	98%	Storage	Store at 4-8°C
Description	Elafibranor is an agonist of the peroxisome proliferator-activated receptor-α and peroxisome proliferator-activated receptor-δ. Elafibranor improves insulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation.We assessed the safety and efficacy of elafibranor in an international, randomized, double-blind placebo-controlled trial of patients with nonalcoholic steatohepatitis (NASH). Elafibranor (GFT505) is a dual PPARα/δ agonist that has demonstrated efficacy in disease models of nonalcoholic fatty liver disease (NAFLD)/NASH and liver fibrosis. Elafibranor confers liver protection by acting on several pathways involved in NASH pathogenesis, reducing steatosis, inflammation, and fibrosis.