CNV-1014802
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CAS No. | 934240-30-9 | Cat. No. | BCP07060 |
Name | CNV-1014802 | ||
Synonyms | GSK-1014802;GSK 1014802;GSK1014802;CNV1014802;CNV 1014802;Raxatrigine; | ||
SMILES | |||
Chemical Name | |||
Formula | C18H19FN2O2 | M. Wt | 314.35 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Raxatrigine, also known as GSK1014802 and CNV-1014802, is a sodium channel antagonist that is currently in phase II studies in bipolar depression. CNV1014802 is a peripherally and centrally acting agent that inhibits sodium channels in a state-dependent fashion. CNV1014802 shows selectivity for the Nav1.7 subtype over the other subtypes tested (Nav1.1, Nav1.2, Nav1.3, Nav1.5, Nav1.6 and TTX-R), for both the resting and depolarized states. |
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