TAK-901 New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP02526CAS No. ：934541-31-8Purity：98%

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CAS No.	934541-31-8	Cat. No.	BCP02526
Name	TAK-901
Synonyms	TAK901;TAK 901;
SMILES	O=C(C1=C(C)C2=C(C(C3=CC=CC(S(=O)(CC)=O)=C3)=C1)C4=CC(C)=CN=C4N2)NC5CCN(C)CC5
Chemical Name
Formula	C28H32N4O3S	M. Wt	504.66
Purity	98%	Storage	Store at 4-8°C
Description	TAK-901 is a small-molecule inhibitor of the serine-threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK-901 binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to each daughter cell; and the separation of daughter cells during cytokinesis. This serine/threonine kinase may be amplified and overexpressed by a variety of cancer cell types. Check for active clinical trials or closed clinical trials using this agent.