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SKQ1
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CAS No. | 934826-68-3 | Cat. No. | BCP15201 |
Name | SKQ1 | ||
Synonyms | SKQ-1;SKQ 1;Visomitin; PDTP; Plastoquinonyl decyltriphenyl phosphonium bromide; | ||
SMILES | O=C(C(CCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=C4)C(C)=C(C)C4=O.[Br-] | ||
Chemical Name | |||
Formula | C36H42BrO2P | M. Wt | 617.6 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SKQ1, also known as Visomitin, is a potent mitochondria-targeted antioxidant. SKQ1 is also an API for making eye drop drug called Visomitin. SKQ1 showed activities (1) to prevent amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices; (2) to reverse aging-related biomarkers in rats; (3) to slow down the development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats; (4) to increase the lifespan of male rodents under LP or SPF conditions. SKQ1 can penetrate cell membranes , and is proposed as an anti-aging treatment. Visomitin, which API is SKQ1, is currently under clinical trials for treating glaucoma in Russia. Note: For the convenience of use, SKQ1 is supplied as solution of 200mg / mL in ethanol-water (1:1, v/v). |
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