GSK690693
Data Sheet
For research use only. Not for human use.
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| CAS No. | 937174-76-0 | Cat. No. | BCP01721 |
| Name | GSK690693 | ||
| Synonyms | GSK-690693;GSK 690693; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C21H27N7O3 | M. Wt | 425.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GSK461364 inhibits cancer cell line proliferation from multiple origins with minimal toxicity in nondividing human cells. [1] RNA silencing of WT p53 increases the antiproliferative activity of GSK461364. As many cancer therapies tend to be more effective in p53 WT patients, the higher sensitivity of p53-deficient tumors toward GSK461364 could potentially offer an opportunity to treat tumors that are refractory to other chemotherapies as well as early line therapy for these genotypes. GSK461364 i | ||
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