Amiselimod hydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 942398-84-7 | Cat. No. | BCP18775 |
| Name | Amiselimod hydrochloride | ||
| Synonyms | MT-1303 HCl; MT1303 HCl; MT 1303 HCl; Amiselimod HCl; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C19H31ClF3NO3 | M. Wt | 413.91 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Amiselimod is a prodrug that is converted to (S)-amiselimod phosphate by sphingosine kinases.Amiselimod phosphate is a highly selective S1P1 receptor antagonist (EC50 = 74 pM) that is without activity at S1P3 receptors. It is approximately five-fold weaker as an activator of G protein-coupled inwardly rectifying K+ (GIRK) channels than fingolimod phosphate.1 Amiselimod is orally bioavailable and has minimal cardiac effects when tested clinically. | ||
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