A-803467
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CAS No. | 944261-79-4 | Cat. No. | BCP04519 |
Name | A-803467 | ||
Synonyms | A803467; A 803467; | ||
SMILES | |||
Chemical Name | |||
Formula | C19H16ClNO4 | M. Wt | 357.79 |
Purity | 98% | Storage | Store at 4-8°C |
Description | A 803467 is a selective Nav1.8 sodium channel blocker and analgesic. A 803467 blocks Nav1.8 with an IC50 of 8 nM and is over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7. A 803467 dose-dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models. |
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