Batefenterol succinate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 945905-37-3 | Cat. No. | BCP19637 |
| Name | Batefenterol succinate | ||
| Synonyms | GSK961081; GSK-961081; GSK 961081; TD-5959; TD 5959; TD5959; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C40H42ClN5O7.C4H6O4 | M. Wt | 858.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Batefenterol, also known as GSK961081 and TD-5959, is a Muscarinic Antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA). GSK-961081 displayed high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). GSK-961081 behaved as a potent hβ2-adrenoceptor agonist (EC50 = 0.29 nM for stimulation of cAMP levels) with 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors, respectively. | ||
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