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GDC-0941 Bimesylate Chemical Structure

GDC-0941 Bimesylate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP13802CAS No. :957054-33-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 957054-33-0 Cat. No. BCP13802
Name GDC-0941 Bimesylate
Synonyms GDC-0941 2 MeSO3H salt;Pictilisib dimethanesulfonate;GDC 0941 Bimesylate;GDC0941 Bimesylate;
SMILES
Chemical Name
Formula C24H30N7O6S3 M. Wt 608.73
Purity 98% Storage Store at 4-8°C
Description GDC-0941 is a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer. GDC-0941 against p110a IC50=0.003μM,U87MG IC50=0.95μM, A2780 IC50=0.14 μM, and in vitro metabolic stability in mouse and human is 91.96%. The inhibitions of U87MG , PC3, MDA-MB-361 cancer cell proliferation are (IC50) 0.95, 0.28, 0.72 μM, respectively.
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