GDC-0941 Bimesylate
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CAS No. | 957054-33-0 | Cat. No. | BCP13802 |
Name | GDC-0941 Bimesylate | ||
Synonyms | GDC-0941 2 MeSO3H salt;Pictilisib dimethanesulfonate;GDC 0941 Bimesylate;GDC0941 Bimesylate; | ||
SMILES | |||
Chemical Name | |||
Formula | C24H30N7O6S3 | M. Wt | 608.73 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GDC-0941 is a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer. GDC-0941 against p110a IC50=0.003μM,U87MG IC50=0.95μM, A2780 IC50=0.14 μM, and in vitro metabolic stability in mouse and human is 91.96%. The inhibitions of U87MG , PC3, MDA-MB-361 cancer cell proliferation are (IC50) 0.95, 0.28, 0.72 μM, respectively. |
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