Ebastine Fumarate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 97928-20-6 | Cat. No. | BCP12948 |
| Name | Ebastine Fumarate | ||
| Synonyms | RP64305; RP-64305; RP 64305; LAS W-090; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C36H43NO6 | M. Wt | 585.73 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Ebastine, is a H1 antihistamine with low potential for causing drowsiness. It does not penetrate the blood–brain barrier to a significant amount and thus combines an effective block of the H1 receptor in peripheral tissue with a low incidence of central side effects, i.e. seldom causing sedation or drowsiness. After oral administration, ebastine undergoes extensive first-pass metabolism by hepatic cytochrome P450 3A4 into its active carboxylic acid metabolite, carebastine. This conversion is practically complete. Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathic urticaria. | ||
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