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Citicoline Chemical Structure

Citicoline

Data Sheet For research use only. Not for human use.
Cat. No. :BCP14479CAS No. :987-78-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 987-78-0 Cat. No. BCP14479
Name Citicoline
Synonyms CDP Choline;Choline, CDP;Cytidine 5'-diphosphate choline; Cytidine 5'-diphosphocholine; Cytidine choline diphosphate; Cytidine diphosphate choline; Cytidine diphosphate choline ester; Cyti;
SMILES C[N+](C)(C)CCOP(=O)([O-])OP(=O)(O)OCC1C(C(C(O1)N2C=CC(=NC2=O)N)O)O
Chemical Name
Formula C14H26N4O11P2 M. Wt 488.32
Purity 98% Storage Store at 4-8°C
Description Citicoline is a nutritional supplement and source of choline and cytidine with potential neuroprotective and nootropic activity. Citicoline, also known as cytidine-5-diphosphocholine or CDP-choline, is hydrolyzed into cytidine and choline in the intestine. Following absorption, both cytidine and choline are dispersed, utilized in various biosynthesis pathways, and cross the blood-brain barrier for resynthesis into citicoline in the brain, which is the rate-limiting product in the synthesis of phosphatidylcholine. This agent also increases acetylcholine (Ach), norepinephrine (NE) and dopamine levels in the central nervous system (CNS). In addition, citicoline is involved in the preservation of sphingomyelin and cardiolipin and the restoration of Na+/K+-ATPase activity. Citicoline also increases glutathione synthesis and glutathione reductase activity, and exerts antiapoptotic effects.
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