K-252A New
Data Sheet
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| CAS No. | 99533-80-9 | Cat. No. | BCP16888 |
| Name | K-252A | ||
| Synonyms | K 252A; K252A; SF-2370; SF 2370; SF2370;Antibiotic K 252A; | ||
| SMILES | CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O | ||
| Chemical Name | |||
| Formula | C27H21N3O5 | M. Wt | 467.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | K-252A, also known as SF 2370, is an alkaloid isolated from Nocardiopisis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L, respectively). At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nmol/L). | ||
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