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Product Literature

  • Product: CX-4945

    Headline: LYG-202 Augments Tumor Necrosis Factor-α-Induced Apoptosis via Attenuating Casein Kinase 2-Dependent Nuclear Factor-κB Pathway in HepG2 Cells

    Author: Fei-hong Chen, Na Lu, Hai-wei Zhang, Li Zhao, Li-cheng He, Hao-peng Sun, Qi-dong You, Zhi-yu Li, and Qing-long Guo

  • Product: SU6668

    Headline: Characterization of the Novel Broad-Spectrum Kinase Inhibitor CTx-0294885 As an Affinity Reagent for Mass Spectrometry-Based Kinome Profiling

    Author: Luxi Zhang, Ian P. Holmes, Falko Hochgr?fe, Scott R. Walker, Naveid A. Ali, Emily S. Humphrey, Jianmin Wu, Melanie de Silva, Wilhelmus J. A. Kersten, Theresa Connor, Hendrik Falk, Lynda Allan, Ian P. Street, John D. Bentley , Patricia A. Pilling , Brendon J. Monahan , Thomas S. Peat , and Roger J. Daly

  • Product: Perifosine

    Headline: Perifosine sensitizes curcumin-induced anti-colorectal cancer effects by targeting multiple signaling pathways both in vivo and in vitro

    Author: Min-Bin Chen, Xiao-Yang Wu, Guo-Qing Tao, Chao-Ying Liu, Jian Chen, Li-Qiang Wang andPei-Hua Lu

  • Product: TAE684, crizotinib & BIBW2992

    Headline: Activation of HER Family Signaling as a Mechanism of Acquired Resistance to ALK Inhibitors in EML4-ALK–Positive Non–Small Cell Lung Cancer

    Author: Junko Tanizaki, Isamu Okamoto, Takafumi Okabe, Kazuko Sakai, Kaoru Tanaka, Hidetoshi Hayashi, Hiroyasu Kaneda, Ken Takezawa, Kiyoko Kuwata, Haruka Yamaguchi, Erina Hatashita, Kazuto Nishio, and Kazuhiko Nakagawa

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    Product Category

    PI3K/Akt/mTOR
    Cell Cycle/Checkpoint
    Angiogenesis/Tyrosine Kinase
    Apoptosis Pathway
    PARP/BET
    Aurora/Ksp Pathway
    MAPK Pathway
    Hormone Pathay
    Integrase/CCR5
    Proteases/HSP90/HSP70 Pathway
    Wnt/Hedgehog/Notch Pathway
    Jak/Stat Pathway
    Ca/cAMP/Lipid Signaling Pathway
    Neuro Signaling Pathway
    TGF-beta/Smad Signaling Pathway
    GPCR Pathway
    Ion channel Pathway
    Cytochrome P450 Pathway
    Others Pathway
    Intermediate