Product Pathways
BCP0008 GSK690693
aminofurazan-derived inhibitor of Akt kinases with potential antine
BCP0114 SB431542
Potent and selective inhibitor of the transforming growth factor-ß (TGF-ß) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7.
BCP0054 Enzastaurin
Enzastaurin (Enz) is a potent and selective inhibitor of PKCß with antiproliferative activity.
Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance.
BCP0182 LDN193189(DM3189)
LDN193189(DM3189) is a highly potent small molecule BMP inhibitor.
BCP0268 Ro 31-8425
Ro 31-8425(Bisindoylmaleimide X,HCI salt) is a potent, cell-permeable, reversible, ATP-competitive, and selective protein kinase C inhibitor.
BCP0321 Copper Peptide(GHK-Cu)
Copper Peptide (GHK-Cu), at concentrations of 1 nM, reduces fibroblast secretion of TGF-beta.
BCP0487 LY2157299
Orally active transforming growth factor beta receptor (TGF-βR) kinase inhibitor.
BCP0529 SD 208
Potent, orally active ATP-competitive transforming growthPotent, orally active ATP-competitive transforming growth factor-β receptor 1 (TGF-βRI) inhibitor
BCP000614 Quercetine(Sophoretin)
Quercetin is a PI3K and PKC inhibitor with IC50 of 3.8 μM and 15µg/ml.
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