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BCP0003 GDC-0879
A highly selective,orally bioavailable B-Raf inhibitor.
BCP0017 AT9283
AT9283 is a potent pan-Aurora inhibitor for Aurora A, Aurora B, JAK3, JAK2 and Abl with IC50 of 3 nM, 3 nM, 1.1 nM, 1.2 nM and 4 nM, respectively.
BCP0021 17-DMAG
17-DMAG (Alvespimycin, KOS-1022, NSC 707545) is a potent HSP90 inhibitor with IC50 of 62 nM.
BCP0022 17AAG;Tanespimycin
17AAG is a less toxic analogue of the geldanamycin which binds to Hsp90.
BCP0025 AZD6244(Selumetinib)
A novel inhibitor of MEK1/2 kinases.
BCP0103 PLX4720
PLX-4720 is a B-raf inhibitor with IC50 of 160 nM.
BCP0110 S31-201,NSC74859
S31-201 (NSC 74859) is a chemical probe inhibitor of Stat3 activity.
BCP0111 SB202190
SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α and p38β with IC50 of 50 nM and 100 nM, respectively.
BCP0112 SB203580
SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM and blocks PKB phosphorylation with IC50 of 3-5 μM.
BCP0032 Bortezomib
Bortezomib (PS-341, Velcade) is a potent proteasome inhibitor.
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