Product Pathways
BCP0001 GDC-0941
GDC-0941 is a potent inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ ;10G in stock
BCP0004 Gefitinib
Gefitinib was found to be a potent inhibitor of EGFR kinase.
BCP0016 AG-490
AG490 is a member of the tryphostin family of tyrosine kinase inhibitors.
BCP0017 AT9283
AT9283 is a potent pan-Aurora inhibitor for Aurora A, Aurora B, JAK3, JAK2 and Abl with IC50 of 3 nM, 3 nM, 1.1 nM, 1.2 nM and 4 nM, respectively.
BCP0020 AZD1152
AZD1152 is 1000-fold more selective for aurora kinase B than for aurora kinase A with Ki values of 1300 nM and 0.36 nM for aurora kinase A and B, respectively.
BCP0023 AZD1152-HQPA(Barasertib)
AZD1152 is a dihydrogen phosphate prodrug of a pyrazoloquinazoline Aurora kinase inhibitor.
BCP0099 Danusertib(PHA-739358)
Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.
BCP0118 SNS-314
SNS-314 is an ATP-competitive, potent and selective inhibitor of Aurora kinases A (IC50=9.0nM), B (IC50=31nM), and C (IC50=3.4nM).
BCP0030 BIBW2992
BIBW-2992 is a potent oral, irreversible combined EGFR/HER2 inhibitor.
BCP0031 BMS-599626(HCl)
BMS-599626,an orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
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