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BCP0013 ABT-888(Veliparib)
ABT-888 (Veliparib) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.
BCP0015 AG-014699
AG014699 is a tricyclic indole poly(ADP-Ribose) polymerase (PARP) inhibitor with potential antineoplastic activity.
BCP0029 BIBF1120
BIBF 1120 is an indolinone derivative potently blocking VEGF receptor (VEGFR), PDGFR and FGFR kinase activity in enzymatic assays (IC50, 20-100 nmol/L).
BCP0099 Danusertib(PHA-739358)
Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.
BCP0036 BSI-201(Iniparib)
BSI-201 is a small molecule believed to achieve its anti-neoplastic effect by covalently binding and inhibiting PARP-1.
BCP0037 BSI-401
BSI-401, a novel PARP-1 inhibitor with both oral bioavailability and strong antitumor potency.
BCP0061 INO-1001
INO-1001 is an isoindolinone derivative and potent inhibitor of the nuclear enzyme PARP (poly (ADP-ribose) polymerase) with chemosensitization and radiosensitization properties.
BCP0149 AZD2281(olaparib)
AZD2281(olaparib) is a highly potent and selective phtalazinone-type PARP-inhibitor with IC 50 of 5nM (PARP-1) and 1 nM (PARP-2).
BCP0218 A-966492(A966492)
A-966492,displayed excellent potency against the PARP-1 enzyme with a Ki of 1 nM and an EC50 of 1 nM in a whole cell assay.
BCP0251 SU5402
SU5402 is a multiple target inhibitor of VEGFR2 (Flk-1/KDR) and FGFR1.
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