Product Pathways
BCP0029 BIBF1120
BIBF 1120 is an indolinone derivative potently blocking VEGF receptor (VEGFR), PDGFR and FGFR kinase activity in enzymatic assays (IC50, 20-100 nmol/L).
BCP0099 Danusertib(PHA-739358)
Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.
BCP0251 SU5402
SU5402 is a multiple target inhibitor of VEGFR2 (Flk-1/KDR) and FGFR1.
BCP0276 CHIR-258(Dovitinib)
Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β.
BCP0345 AP24534(Ponatinib)
AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively.
BCP000694 PD173074
Selective FGFR1 and FGFR3 inhibitor.
BCP000888 AZD4547/AZD-4547
BCP001259 AZD4547
BCP001387 LY2874455
BCP001600 Vargatef
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