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BCP0205 R406
R406,an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation R406 bound to the ATP binding pocket of Syk and inhibited its kinase activity as an ATP-competitive inhibitor (Ki = 30 nM).
BCP000632 Fostamatinib
Fostamatinib (R788) is an important spleen tyrosine kinase (Syk) inhibitor and a free base of R935788 (FosD, fostamatinib disodium
BCP000977 R935788 (Fostamatinib disodium)
BCP001666 P505-15
Highly specific and potent inhibitor of spleen tyrosine kinase (Syk) (IC50: 1-2 nM).
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