Product Pathways
BCP0021 17-DMAG
17-DMAG (Alvespimycin, KOS-1022, NSC 707545) is a potent HSP90 inhibitor with IC50 of 62 nM.
BCP0022 17AAG;Tanespimycin
17AAG is a less toxic analogue of the geldanamycin which binds to Hsp90.
BCP0052 Elesclomol
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells.
BCP0081 NVP-AUY922
NVP-AUY922 (VER-52296) is a highly potent HSP90 inhibitor for HSP90α and HSP90β with IC50 of 13 nM and 21 nM, respectively.
BCP0385 17-DMAG
17-DMAG, a watersoluble geldanamycin analog belonging to the class of benzoquinones, is a selective Hsp90 inhibitor.
BCP0410 Atazanavir(BMS-232632)
Atazanavir (Reyataz, BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class.
BCP0420 BIIB021
BIIB021,formerly CNF2024,is a novel fully synthetic inhibitor of Hsp90.
BCP000726 Geldanamycin
Geldanamycin,Selectively inhibits heat shock protein 90 (Hsp90).
BCP000749 SNX5422
PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and also inhibits Her-2 degradation with IC50 of 37 nM.
BCP000788 NVP-BEP800
NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor with an IC50 of 0.058 0.006 ?M.
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