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BCP0107 Rapamycin
Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor.
BCP0045 CP690550(Tasocitinib)
CP690550(Tasocitinib),the only Janus Kinase 3 (JAK3) inhibitor currently in clinical trials,an immunosuppressive agent exhibiting potent effects in preclinical transplantation and arthritis models.
BCP0056 Everolimus(RAD001)
Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.
BCP0057 FK-506
An immunosuppressive agent and macrolide antibiotic.
BCP0058 FTY720
FTY720 (Fingolimod, Gilenya) is a S1P antagonist.
BCP0136 VX702
VX-702, one of a series of second-generation, orally active p38 MAP kinase inhibitors, for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases.
BCP0205 R406
R406,an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation R406 bound to the ATP binding pocket of Syk and inhibited its kinase activity as an ATP-competitive inhibitor (Ki = 30 nM).
BCP0328 Mycophenolate mofetil(CellCept)
Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively.
BCP0387 Abitrexate(Methotrexate)
Abitrexate (Methotrexate) is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.
BCP0462 Darunavir Ethanolate(Prezista)
Darunavir Ethanolate(Prezista) is an inhibitor of HIV protease.
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