Product Pathways
BCP0007 GSK461364
GSK461364 is an ATP-competitive inhibitor of Plk1 and forms a rapidly reversible complex with Plk1.
BCP0028 BI2536
Potent and selective polo-like kinase (PLK) 1 inhibitor.
BCP0131 LY315920(Varespladib)
Varespladib is a selective inhibitor of human, group IIA, nonpancreatic secretory PLA2 (sPLA2).
BCP0186 GW843682X
Selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3).
BCP0350 HMN-214(IVX-214)
HMN-214(a prodrug of HMN-176) is a potent PLK1 inhibitor.
BCP000728 BI6727 (Volasertib)
BI 6727 is a highly potent Polo-like kinase inhibitor.
BCP000979 ON-01910
BCP001396 ICRF193
BCP001424 Darapladib
The lead compound 7 (RO3280) has potent inhibitory activity against PLK1, good selectivity against other kinases, and excellent in vitro cellular potency.
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