Product Pathways
BCP0009 Abiraterone(CB-7598)
A steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase inhibitor
BCP0010 ABT-263(Navitoclax)
ABT-263 (Navitoclax) is a potent orally bioavailable SMI that is structurally related to ABT-737. ABT-263 disrupts Bcl-2 - Bcl-XL interactions with pro-apoptotic proteins .
BCP0011 ABT737
ABT737,a selective inhibitor of BCL-2, in small cell lung cancer.
BCP0013 ABT-888(Veliparib)
ABT-888 (Veliparib) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.
BCP0016 AG-490
AG490 is a member of the tryphostin family of tyrosine kinase inhibitors.
BCP0018 Axitinib
a small molecule tyrosine kinase inhibitor under development by Pfi
BCP0020 AZD1152
AZD1152 is 1000-fold more selective for aurora kinase B than for aurora kinase A with Ki values of 1300 nM and 0.36 nM for aurora kinase A and B, respectively.
BCP0023 AZD1152-HQPA(Barasertib)
AZD1152 is a dihydrogen phosphate prodrug of a pyrazoloquinazoline Aurora kinase inhibitor.
BCP0025 AZD6244(Selumetinib)
A novel inhibitor of MEK1/2 kinases.
BCP0026 Belinostat
Belinostat (PXD101) is a novel hydroxamate-type inhibitor of histone deacetylase (HDAC) activity.
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