Naratriptan hydrochloride New
Data Sheet
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| CAS No. | 143388-64-1 | Cat. No. | BCP04270 |
| Name | Naratriptan hydrochloride | ||
| Synonyms | Naratriptan HCl;Amerge hydrochloride;GR-85548A hydrochloride;Naramig hydrochloride; | ||
| SMILES | CNS(=O)(=O)CCC1=CC2=C(C=C1)NC=C2C3CCN(CC3)C.Cl | ||
| Chemical Name | |||
| Formula | C17H25N3O2S.HCl | M. Wt | 371.93 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride binds selectively and with high affinity to the 5-HT1D and 5-HT1B receptor subtypes. Activation of these 5-HT1D/B receptors located on intracranial blood vessels leads to vasoconstriction and provides relief of migraine headaches. Naratriptan hydrochloride may also exerts its effect by stimulation of 5-HT1D/1B receptors on sensory nerve endings in the trigeminal system thereby decreasing the release of pro-inflammatory neuropeptides. | ||
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