Cas No.Product NameDescription
601514-19-6TWS119TWS119 is inhibitor of glycogen synthase kinase-3β (IC50 = 30 nM).
612487-72-6AZD1080AZD1080 is a potent and selective GSK3 inhibitor.
486424-20-8AZD2858AZD2858 is a selective GSK-3 inhibitor .
280744-09-4SB216763SB 216763 is potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 9 nM for GSK-3α); competes with ATP.
252917-06-9CHIR99021CHIR-99021 (CT99021) is a GSK-3 inhibitor, IC50= 7 nM
264218-23-7SB415286SB-415286 is an ATP-competitive inhibitor of Glycogen Synthase Kinase 3α (GSK3α) with a Ki value of 31 nM.
865854-05-3Tideglusib Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor with IC50 of 60 nM; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 1/2.
603288-22-8 LY2090314LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3).
487021-52-3AR-A 014418AR-A014418 is a effective GSK3 inhibitor.
585543-15-3losmapimod ;GW-856553Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively.
1129669-05-1IM-12 IM-12 is a potent GSK-3β inhibitor with IC50 of 53 nM; shows a significant activity in several biological tests which was comparable or even outplayed the effects of the known SB-216763.
188011-69-0BikininBikinin is an ATP-competitive Arabidopsis GSK-3 inhibitor, and acts as a strong activator of brassinosteroid (BR) signaling.
752187-80-7CP544326Taprenepag, also known as CP-544326, is a potent and selective EP(2) receptor agonist, was successfully evaluated for its ocular hypotensive activity in a clinical study involving patients with primary open angle glaucoma.
912806-16-7BMS-582949 hydrochlorideBMS-582949 hydrochloride is a novel highly selective p38α MAPK inhibitor, inhibits p38α with IC50 of 13 nM.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway