Products

Cas No.Product NameDescription
929095-18-1GSK461364GSK461364 is a potent small molecule Polo-like kinase 1 (PLK1) inhibitor with a Ki of 2.2 nM.
755038-02-9BI 2536BI 2536 is Plk1 inhibitor with an IC50 of 0.83 nM.
321674-73-1BIBR-1532BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively).
864082-47-3GSK429286AGSK429286A is a cell-permeable, selective Rho-associated kinase (ROCK) inhibitor with an IC50 of 14 nM.
173529-46-9HMN-214HMN-214 is a potent PLK1 inhibitor an average IC50 of 0.12 μM.
152044-54-7Epothilone BEpothilone B (EPO906, Patupilone) is a Taxol-like microtubule-stabilizing agent with EC0.01 of 1.8 μM.
755038-65-4VolasertibVolasertib is a highly potent Polo-like kinase inhibitor with an IC50 of 0 .87 nM.
630420-16-5BMS 650032Asunaprevir is an inhibitor of the viral enzyme serine protease HCV NS3.
57852-57-0Idarubicin hydrochlorideIdarubicin hydrochloride is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II inhibitor for MCF-7 cells with an IC50 of 3.3 ng/mL.
186692-46-6RoscovitineRoscovitine (Seliciclib) is a potent and selective inhibitor of cyclin-dependent kinases. This agent displays higher inhibitory potency and higher selectivity compared to olomoucine.
154361-50-9CapecitabineCapecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers.
114977-28-5DocetaxelDocetaxel, an analog of taxol, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.
33069-62-4PaclitaxelxPaclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
827022-32-2Palbociclib HClPalbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
136572-09-3Irinotecan HCl TrihydrateThe anticancer agent, Irinotecan, is a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.
955365-80-7MK-1775MK-1775 is a potent and selective Wee1 kinase inhibitor with an IC50 of 5.2 nM.
345627-80-7SNS-032 BMS-387032 is a potent inhibitor of cyclin-dependent kinases (cdks) 9, 2 and 7 (IC50 values are 4, 38 and 62 nM respectively).
372196-67-3PIK-75PIK-75, free base is a selective inhibitor of PI 3-kinase p110α (IC50 values are 5.8, 76 nM and 1.3 μM at PI 3-kinase p110α, PI 3-kinase p110γ and PI 3-kinase p110β respectively).
718630-59-2PHA-793887PHA-793887 is a novel pan-cdk inhibitor, including cdk1, cdk2, cdk4, cdk5, cdk7, and cdk9 with IC50 in the 5 to 140 nM range.
25316-40-9Doxorubicin HClDoxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.

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PI3K/Akt/mTOR
Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
PARP/BET
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Integrase/CCR5
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway
Intermediate