Cas No.Product NameDescription
372196-67-3PIK-75PIK-75, free base is a selective inhibitor of PI 3-kinase p110α (IC50 values are 5.8, 76 nM and 1.3 μM at PI 3-kinase p110α, PI 3-kinase p110γ and PI 3-kinase p110β respectively).
121032-29-9NelarabineNelarabine (Arranon, 506U78) is a purine nucleoside analog and DNA synthesis inhibitor.
1138549-36-6CX-5461CX-5461 is a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage.
81103-11-9ClarithromycinClarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor.
147-94-4CytarabineCytarabine (Cytosine arabinoside, AraC) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells.
2022-85-7FlucytosineFlucytosine (5-Fluorocytosine, 5-FC) is an antifungal drug with IC50 of 0.93 μM in C. albicans.
50924-49-7MizoribineMizoribine is a immunosuppressive agents (IC50=100 uM) that inhibit the proliferation of lymphocytes selectively, via inhibition of IMPDH.
366-70-1Procarbazine hydrochlorideProcarbazine HCl, an antineoplastic chemotherapy drug, is an alkylating agent for the treatment of Hodgkin's lymphoma and certain brain cancers; also inhibits MAO thus increasing the effects of sympathomimetics, TCAs, and tyramine.
723-46-6SulfamethoxazoleSulfamethoxazole is a sulfonamide bacteriostatic antibiotic.
72496-41-4PirarubicinAn analogue of the anthracycline anti-neoplastic doxorubicin.
165800-03-3LinezolidLinezolid is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics.
74588-78-6D-6413D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with colchicine to αβ-Tubulin.
92118-27-9FotemustineFotemustine (S 10036) is a nitrosourea alkylating agent approved for use in the treatment of metastasising melanoma.
192441-08-0LomeguatribInhibitor of O6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 μM in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo.
1247819-59-5P22077P22077 is a potent inhibitor of ubiquitin-specific protease (USP) 7 (EC50=8.6 uM), P22077 also inhibits the closely related deubiquitinase USP47.
50935-04-1CarubicinCarubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata.
415713-60-9RI-1RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.
1011557-82-6Tenovin-6 Tenovin-6 is the water soluble analog of Tenovin-1 and acts as a potent SIRT1 and SIRT2 inhibitor as well as p53 activator.
516480-79-8Chk2 Inhibitor IIBML-277 (Chk2 Inhibitor II) is a Chk2 (checkpoint kinase 2) inhibitor.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway