Cas No.Product NameDescription
1025720-94-8BMS-777607BMS-777607, a Met tyrosine kinase inhibitor.
875337-44-3MGCD-265MGCD-265 is a multi-targeted kinase inhibitor, which targets the c-MET, VEGFR1, VEGFR2, VEGFR3, Tie-2 and Ron receptor tyrosine kinases.
877399-52-5CrizotinibCrizotinib is inhibitor of the c-Met kinase and the NPM-ALK.
477575-56-7PHA-665752PHA-665752 is potent, selective and ATP-competitive inhibitor of MET kinase.
1022150-57-7SGX-523SGX-523 is an exquisitely selective, ATP-competitive MET receptor tyrosine kinase inhibitor with an IC50 of 4 nM for the inhibition of HGFR.
658084-23-2SU11274SU11274 is selective inhibitor of MET tyrosine kinase activity (IC50 = 0.01 μM in vitro).
943540-75-8JNJ-38877605JNJ-38877605 is a c-MET inhibitor with an IC50 of 4 nM.
956905-27-4PF-04217903PF-04217903 is MET inhibitor with an IC50 from 3.1 nM to142 nM. A potent, selective (>1000-fold more selective than other 208 kinases), orally bioavailable c-Met kinase inhibitor with Ki at low nM.
913376-83-7AMG458AMG 458 also inhibits HGF-mediated c-Met phosphorylation in PC3 and CT26 cells with IC50 of 60 and 120 nM.
319460-94-1AG13958AG13958 is a VEGFR inhibitor in clinical development for treatment of age-related macular degeneration.
956906-93-7PF-04217903 mesylatePF 04217903 mesylate is a selective ATP-competitive Met inhibitor with IC50 of 4.8 nM.
849217-64-7ForetinibForetinib is an ATP-competitive active site inhibitor of tyrosine kinases including Flt-1, Flt-4, Met, and Ron.
905854-02-6TivantinibTivantinib is an orally available, small molecule inhibitor of the c-Met receptor tyrosine kinase.
1021950-26-4Tyrosine kinase inhibitorA Tyrosine kinase inhibitor.
928037-13-2E7050E-7050 is hepatocyte growth factor receptors (HGFR).
1206799-15-6LY2801653 LY2801653 is a potent, orally bioavailable, small-molecule inhibitorLY2801653 targeting MET kinase.
1100598-32-0EMD-1214063EMD 1214063 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity.
176161-24-3MaribavirMaribavir(GW257406X; BW1263W94; 1263W94) inhibits HCMV replication is by inhibition of an HCMV encoded protein kinase enzyme called UL97 or pUL97.
1313725-88-0VolitinibSavolitinib, also known as Volitinib, AZD6094 or HMPL-504, is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity. rotein.
873786-09-5PLX647PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respectively.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway