Cas No.Product NameDescription
1346704-33-3GSK343GSK343 is a specific inhibitor of EZH2 methyltransferase, which can decrease the level of H3K27Me3, the product of EZH2's enzymatic activity.
50-41-9Clomifene citrateClomifene Citrate is a selective estrogen receptor modulator.
129453-61-8Fulvestrant Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM.
84-16-2HexestrolHexestrol binds to ERα and ERβ with EC50 of 0.07 nM and 0.175 nM, respectively.
54965-24-1Tamoxifen citrateTamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen.
68392-35-8Afimoxifene4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.
198062-54-3GW311616GW311616 is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase(HNE) with IC50 of 22 nM; free base form of GW311616A.
112093-28-4EndoxifenEndoxifen is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα). Endoxifen inhibits hERG tail currents at 50 mV in a concentration-dependent manner with IC50 values of 1.6 μM.
1197194-61-8Endoxifen E-isomer hydrochlorideEndoxifen (E-isomer hydrochloride) is a tamoxifen metabolite and potent Selective Estrogen Response Modifier.
1598383-41-5EPZ011989 trifluoroacetate
1588521-78-1BET-BAY 002BET-BAY 002 is a potent BET inhibitor; shows efficacy in a multiple myeloma model.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway