Cas No.Product NameDescription
871038-72-1Raltegravir potassiumRaltegravir Potassium Salt is a potent human immunodeficiency virus (HIV) integrase inhibitor
697761-98-1ElvitegravirElvitegravir is a human immunodeficiency virus integrase inhibitor with EC50 of 0.7, 2.8 and 1.4 for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD.
1051375-16-6DolutegravirDolutegravir is an integrase inhibitor being developed for the treatment of human immunodeficiency virus (HIV)-1 infection by GlaxoSmithKline (GSK) on behalf of Shionogi-ViiV Healthcare LLC.
376348-65-1MaravirocMaraviroc is a Selective CCR5 antagonist; displays potent anti-HIV-1 activity.
541503-81-5Vicriviroc MalateVicriviroc Malate is a potent CCR5 antagonist with IC50 of 0.91 nM.
729607-74-3BMS-707035BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM.
2645-32-1 PR-619PR-619 is a broad-range DUB inhibitor with potential for further development as a chemotherapeutic agent in cancer therapy.
307510-92-5CFTRinh-172CFTR(inh)-172 is an reversibly inhibitor of CFTR short-circuit current in less than 2 minutes in a voltage-independent manner with Ki approximately 300 nM.
1109276-89-2PF-04620110PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
1173022-16-6RS-102895 hydrochlorideRS102895 Hcl is a potent and specific CCR2 antagonist with binding IC50 of 360 nM, no significant inhibition on CCR1(IC50 > 17 uM).
1134822-09-5Ivacaftor benzenesulfonateIvacaftor benzenesulfonate (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.
917497-70-2SC144 hydrochlorideSC144 hydrochloride is the first-in-class orally active small-molecule gp130 inhibitor; inhibits cell growth in a panel of human ovarian cancer cell lines with IC50 values in a submicromolar range.
140926-75-6NSC5844NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway