Products

Cas No.Product NameDescription
348622-88-8UK 383367UK-383367 (UK 383367) is a Potent and selective inhibitor of BMP-1 (procollagen C-proteinase; PCP) (IC50 = 44 nM).
1009119-64-5DaclatasvirDaclatasvir (BMS-790052; EBP 883) is a first-in-class, highly-selective oral HCV NS5A inhibitor.
133407-82-6MG-132MG-132 displays >1000 times more activity than ZLLal in inhibiting the ZLLL-MCA-degrading activity of 20S proteasome with IC50 of 100 nM versus 110 μM.
819812-04-9KW-2478KW-2478 inhibits the binding of bRD to Hsp90α with IC50 of 3.8 nM.
7497-07-6NSC 405020Membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L). D
488832-69-5ElesclomolElesclomol in the new strong oxidizing stress induced.
75747-14-717-AAG17-AAG is a less toxic analogue of the geldanamycin which binds to Hsp90 and alters its function.
179324-69-7BortezomibBortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM.
747412-49-3AUY922NVP-AUY922, a novel resorcinylic isoxazole amide heat shock protein 90 (HSP90) inhibitor.
229975-97-7Atazanavir sulfateAtazanavir Sulfate is a sulfate salt form of atazanavir (BMS-232632) that is an highly potent HIV protease inhibitor with an EC50 and EC90 of 2.6~5.3 nM and 9~15 nM in cell culture.
238750-77-1Chr-2797CHR-2797 is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2.
1072833-77-2MLN2238MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM, respectively, also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites, with IC50 of 31 and 3500 nM.
1201902-80-8MLN 9708 analog;MLN-9708 analogMLN9708 immediately hydrolyzed to MLN2238, which is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the 20S proteasome with an IC50 value of 3.4 nM (Ki = 0.93 nM).
908115-27-5SNX-5422PF-04929113 is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.
155213-67-5RitonavirRitonavir is an antiretroviral drug which inhibits a particular liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4).
908112-43-6SNX-2112SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, uniformly more potent than 17-AAG.
58970-76-6UbenimexUbenimex is a competitive aminopeptidase B inhibitor with an IC50 of 100 mg/ml for K562 cells.
1092540-56-1 Deuterated Atazanivir-D3-1Atazanivir-D3-2 is a azapeptide derivative and inhibits HIV protease.
850649-61-5 AlogliptinAlogliptin is an orally administered, anti-diabetic drug in the DPP-4 inhibitor class.
161814-49-9AmprenavirAmprenavir is an HIV protease inhibitor with IC50 of 14.6 ng/mL in wild-type HIV isolates.

First Previous Next End   Jump to  Page
PI3K/Akt/mTOR
Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
PARP/BET
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Integrase/CCR5
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway
Intermediate