Cas No.Product NameDescription
635318-11-5LY404039LY404039 is a potent agonist of recombinant human mGluR-2, mGluR-3 receptors with Ki of 149 nM, and 92 nM respectively.
956697-53-3ErismodegibLDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity.
244218-51-7JTC-801 HClJTC-801 is a novel high affinity, selective opioid receptor-like1 receptor antagonist with a Ki of 8.2 nM.
2854-32-2BML 190BML-190 is a selective CB2 inverse agonist with Ki of 435 nM.
461432-26-8Dapagliflozina drug used to treat type 2 diabetes
104344-23-2Bisoprolol FumarateBisoprolol fumarate is a selective type β1 adrenergic receptor blocker.
67469-78-7Vanoxerine dihydrochlorideVanoxerine 2 Hcl(GBR12909) is a potent and selective DRI (Dopamine reuptake inhibitor).
1028969-49-4MCOPPB trihydrochlorideMCOPPB trihydrochloride is a high affinity NOP receptor (KOR-3) agonist.
192927-92-7LY310762 HClLY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM, having a weaker affinity for 5-HT1B receptor.
21102-95-4BMY7378 HClBMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.
851881-60-2ADX-47273ADX-47273 is a novel, potent and selective metabotropic glutamate receptor 5 allosteric modulator with an EC50 of 170 nM.
123464-89-1PNU282987PNU-282,987 is a highly selective agonist for the homomeric α7 nicotinic acetylcholine receptor (α7 nAChR).
146362-70-1SR 48692SR 48692 is a neurotensin antagonist that displays selectivity for NTS1 over NTS2.
71119-11-4BucindololBucindolol is a non-selective β-AR adrenoceptor antagonist with additional α1A-AR adrenoceptor blocking activity. Ki values are 1.61, 1.20 and 68.9 nM for β1-AR (β1-), β2-AR(β2-) and α1A-AR (α1-adrenoceptors), respectively.
616202-92-7LorcaserinLorcaserin is a highly selective 5-HT2C receptor agonist developed for the treatment of obesity.
104075-48-1Atipamezole hydrochlorideA selective α2-adrenergic receptor antagonist (Ki values are 1.1, 1.0, 0.89, 1300 and 6500 nM for α2A, α2B, α2C, α1A and α1B receptors respectively).
89365-50-4SalmeterolSalmeterol is a long-acting beta2-adrenergic receptor (beta 2AR) agonist used clinically to treat asthma.
638-94-8DesonideDesonide is a nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
132810-10-7BlonanserinBlonanserin(AD-5423) is a D2/5-HT2 receptor antagonist, atypical antipsychotic.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway