Cas No.Product NameDescription
635318-11-5LY404039LY404039 is a potent agonist of recombinant human mGluR-2, mGluR-3 receptors with Ki of 149 nM, and 92 nM respectively.
851881-60-2ADX-47273ADX-47273 is a novel, potent and selective metabotropic glutamate receptor 5 allosteric modulator with an EC50 of 170 nM.
433967-28-3VU0357121VU0357121 is a novel positive allosteric modulator (PAM) of mGlu5 with EC50 of 33 nM, is inactive or very weakly antagonizing at other mGlu receptor subtypes.
121062-08-6Melanotan IIMelanotan II is an analog of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH).
96206-92-7MPEP hydrochlorideMPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.
1246086-78-1VU 0364439Positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
55778-02-4WZ 811WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.
83919-23-7Mometasone furoateMometasone furoate, prodrug of the free form mometasone, is a agent with high affinity for the glucocorticoid receptor.
141758-74-9Exendin-4Exendin-4, a 39 amino acid peptide, activates GLP-1 (glucagon-like peptide-1) receptors to increase intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors.
869113-09-7Umeclidinium bromideUmeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD).
540769-28-6PalosuranPalosuran (ACT-058362) is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM.
864864-17-5CFMTICFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist with IC50 of 2.6 nM.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway