Products

Cas No.Product NameDescription
1380288-87-8EPZ5676EPZ-5676 is a potent and selective aminonucleoside inhibitor.
878141-96-9S1RAS1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM).
289905-88-0TRAM-34TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM).
873054-44-5Ivacaftor;KalydecoIvacaftor is a CFTR activator (IC50 of 43 ± 38 nM).
175481-36-4LacosamideLacosamide (Vimpat; Erlosamide) is a medication developed for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.
284035-33-2NPS 2143NPS 2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.
30484-77-6Flunarizine 2HClFlunarizine is a selective calcium entry blocker.
518-34-3TetrandrineTetrandrine, a bis-benzylisoquinoline alkaloid derived from Stephania tetrandra, is a calcium channel blocker.
944261-79-4A-803467 a selective Nav1.8 sodium channel blocker and analgesic
57-41-0PhenytoinPhenytoin is an inactive voltage-gated sodium channel stabilizer.
205645-02-9NS-1209
162831-31-4IEM1754 dihydrobromideIEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
376594-67-1LY450108LY450108 is an alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor potentiator.
2627-69-2AcadesineA cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis.
41332-24-5NP-118809 NP-118809 is a potent N-type calcium channel blockers which have good selectivity over L-type calcium channels.
1191252-49-9IOWH-032iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 .
474645-27-7MonoMethyl auristatin EMonomethyl auristatin E is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.
1393477-72-9/1421923-86-5KPT-330KPT-330 is an orally bioavailable selective CRM1 inhibitor.
931706-15-9PPQ-102CFTR Inhibitor IV, PPQ-102 is a compound that targets intracellular nucleotide binding domain(s) of CFTR and inhibits CFTR- mediated chloride current in a voltage-dependent and reversible manner.
138977-28-3CapsazepineCapsazepine is a synthetic analogue of the sensory neurone excitotoxin, capsaicin; potent TRPV1 receptor antagonist with IC50 of 562 nM.

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PI3K/Akt/mTOR
Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
PARP/BET
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Integrase/CCR5
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
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Intermediate