(±)-SLV319

  • Chemical Properties
CAS No. 362519-49-1 Cat. No. BCP30069
Name (±)-SLV319
Synonyms (±)-BMS-646256; (±)-BMS646256; (±)-BMS 646256; (±)-SLV-319; (±)-SLV 319; SLV319; (±)-JD-5001; (±)-JD 5001; (±)-JD5001; (±)-Ibipinabant;
Formula C23H20Cl2N4O2S M. Wt 487.40
  • Biological Activity
Description (±)-SLV319 is the racemate of SLV319. SLV319 is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM.Ibipinabant, also known as BMS-646256, JD-5001 and SLV-319, is a potent and highly selective CB1 antagonist. It has potent anorectic effects in animals, and was researched for the treatment of obesity, although CB1 antagonists as a class have now fallen out of favour as potential anorectics following the problems seen with rimonabant, and so ibipinabant is now only used for laboratory research, especially structure-activity relationship studies into novel CB1 antagonists.
Pathways GPCR/G Protein 
Targets Cannabinoid Receptor 

Structure

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