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(±)-SLV319 Chemical Structure

(±)-SLV319

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30069CAS No. :362519-49-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 362519-49-1 Cat. No. BCP30069
Name (±)-SLV319
Synonyms (±)-BMS-646256; (±)-BMS646256; (±)-BMS 646256; (±)-SLV-319; (±)-SLV 319; SLV319; (±)-JD-5001; (±)-JD 5001; (±)-JD5001; (±)-Ibipinabant;
SMILES CN=C(NS(=O)(=O)C1=CC=C(C=C1)Cl)N2CC(C(=N2)C3=CC=C(C=C3)Cl)C4=CC=CC=C4
Chemical Name
Formula C23H20Cl2N4O2S M. Wt 487.40
Purity 98% Storage Store at 4-8°C
Description (±)-SLV319 is the racemate of SLV319. SLV319 is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM.Ibipinabant, also known as BMS-646256, JD-5001 and SLV-319, is a potent and highly selective CB1 antagonist. It has potent anorectic effects in animals, and was researched for the treatment of obesity, although CB1 antagonists as a class have now fallen out of favour as potential anorectics following the problems seen with rimonabant, and so ibipinabant is now only used for laboratory research, especially structure-activity relationship studies into novel CB1 antagonists.
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