RBN-2397
| CAS No. | 2381037-82-5 | Cat. No. | BCP33764 |
| Name | RBN-2397 | ||
| Synonyms | RBN2397;RBN 2397; | ||
| Formula | C20H23F6N7O3 | M. Wt | 523.43 |
| Description | RBN-2397 is a potent, accross species and orally active NAD+ competitive inhibitor of PARP7 (IC50<3 nM). RBN-2397 selectively binds to PARP7 (Kd=0.001 μM) and restores interferon (Type I) signaling. RBN-2397 has the potential for the study of advanced or metastatic solid tumors. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | PARP | ||
Structure
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