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RBN-2397 Chemical Structure

RBN-2397

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33764CAS No. :2381037-82-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2381037-82-5 Cat. No. BCP33764
Name RBN-2397
Synonyms RBN2397;RBN 2397;
SMILES O=C1C(C(F)(F)F)=C(N[C@@H](C)COCCC(N2CCN(C3=NC=C(C(F)(F)F)C=N3)CC2)=O)C=NN1
Chemical Name
Formula C20H23F6N7O3 M. Wt 523.43
Purity 98% Storage Store at 4-8°C
Description RBN-2397 is a potent, accross species and orally active NAD+ competitive inhibitor of PARP7 (IC50<3 nM). RBN-2397 selectively binds to PARP7 (Kd=0.001 μM) and restores interferon (Type I) signaling. RBN-2397 has the potential for the study of advanced or metastatic solid tumors.
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