Z-IETD-FMK
| CAS No. | 210344-98-2 | Cat. No. | BCP27867 |
| Name | Z-IETD-FMK | ||
| Synonyms | Z-IE(OMe)TD(OMe)-FMK; Granzyme B Inhibitor III; MDK4982; MDK-4982; MDK 4982; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F;ZIETDFMK; | ||
| Formula | C30H43FN4O11 | M. Wt | 654.68 |
| Description | Z-IETD-FMK, also known as MDK4982, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B., The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. MDK4982 effectively inhibits influenza virus-induced apoptosis in HeLa cells. MDK4982 also inhibits granzyme B. MDK4982 has CAS#210344-98-2. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Caspase | ||
Structure
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