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Z-IETD-FMK Chemical Structure

Z-IETD-FMK

Data Sheet For research use only. Not for human use.
Cat. No. :BCP27867CAS No. :210344-98-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 210344-98-2 Cat. No. BCP27867
Name Z-IETD-FMK
Synonyms Z-IE(OMe)TD(OMe)-FMK; Granzyme B Inhibitor III; MDK4982; MDK-4982; MDK 4982; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F;ZIETDFMK;
SMILES CCC(C(NC(OCC1=CC=CC=C1)=O)C(NC(C(NC(C(NC(C(CF)=O)CC(OC)=O)=O)C(O)C)=O)CCC(OC)=O)=O)C
Chemical Name
Formula C30H43FN4O11 M. Wt 654.68
Purity 98% Storage Store at 4-8°C
Description Z-IETD-FMK, also known as MDK4982, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B., The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. MDK4982 effectively inhibits influenza virus-induced apoptosis in HeLa cells. MDK4982 also inhibits granzyme B. MDK4982 has CAS#210344-98-2.
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