Balicatib

  • Chemical Properties
CAS No. 354813-19-7 Cat. No. BCP09098
Name Balicatib
Synonyms AAE581; AAE-581; AAE 581;
Formula C23H33N5O2 M. Wt 411.54
  • Biological Activity
Description Balicatib, also known as AAE581, is an inhibitor of the osteoclastic enzyme cathepsin K. Balicatib partially prevented ovariectomy-induced changes in bone mass, inhibited bone turnover at most sites, and had an unexpected stimulatory effect on periosteal bone formation.
Pathways Protease/Metabolic Enzyme 
Targets Cathepsin 

Structure

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