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CAS No. | 354813-19-7 | Cat. No. | BCP09098 |
Name | Balicatib | ||
Synonyms | AAE581; AAE-581; AAE 581; | ||
SMILES | O=C(NC1(C(NCC#N)=O)CCCCC1)C2=CC=C(N3CCN(CCC)CC3)C=C2 | ||
Chemical Name | |||
Formula | C23H33N5O2 | M. Wt | 411.54 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Balicatib, also known as AAE581, is an inhibitor of the osteoclastic enzyme cathepsin K. Balicatib partially prevented ovariectomy-induced changes in bone mass, inhibited bone turnover at most sites, and had an unexpected stimulatory effect on periosteal bone formation. |
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