ML347
| CAS No. | 1062368-49-3 | Cat. No. | BCP09855 |
| Name | ML347 | ||
| Synonyms | ML-347;ML 347;DN193719;DN-193719;DN 193719; | ||
| Formula | C22H16N4O | M. Wt | 352.39 |
| Description | ML347 has IC50’s of 46 and 32 nM, respectively, against ALK1 and ALK2; however, the IC50 against ALK3 is 10,800 nM, >300-fold selective over ALK3. ML347 is completely inactive against all the other kinases tested (with weak activity against ALK6, 9830 nM and KDR (VEGFR2)19,700 nM). ML347 is potent in the BMP4 cell assay (152 nM). | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase TGF beta/Smad | ||
| Targets | BMP/TGF beta Receptor ALK | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.