ML347
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1062368-49-3 | Cat. No. | BCP09855 |
| Name | ML347 | ||
| Synonyms | ML-347;ML 347;DN193719;DN-193719;DN 193719; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C22H16N4O | M. Wt | 352.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ML347 has IC50’s of 46 and 32 nM, respectively, against ALK1 and ALK2; however, the IC50 against ALK3 is 10,800 nM, >300-fold selective over ALK3. ML347 is completely inactive against all the other kinases tested (with weak activity against ALK6, 9830 nM and KDR (VEGFR2)19,700 nM). ML347 is potent in the BMP4 cell assay (152 nM). | ||
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